World Rural Health Conference
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 700
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
CASE REPORT
Year : 2013  |  Volume : 2  |  Issue : 1  |  Page : 111-114

Two case reports indicating the dilemma in diagnosing lupus cerebritis


1 Medical Intensive Care Unit, The Misson Hospital, Durgapur, West Bengal, India
2 Department of Medicine, The Misson Hospital, Durgapur, West Bengal, India

Correspondence Address:
Dharitri Goswami
Medical Intensive Care Unit, The Misson Hospital, Ima Kalyan Sarani, Durgapur, West Bengal - 713 212
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2249-4863.109973

Rights and Permissions

Systemic Lupus Erythematosus (SLE) is a connective-tissue disorder commonly affecting females of reproductive age group. Lupus Cerebritis is a serious neurological complication encountered in a good percentage of SLE cases. In this report, we discuss two Lupus Cerebritis patients, who were successfully diagnosed and treated. The first case, presented with generalized seizure, severe metabolic acidosis, and shock, with a history of fever of one-month duration. The second case manifested with an attack of generalized seizure after suffering from low-grade intermittent fever and joint pains for a duration of one-and-a-half months. Central Nervous System (CNS) involvement in SLE is caused by an inflammatory response of the autoimmune system, precipitated by an increased concentration of cytokines. Prompt identification of Lupus Cerebritis is extremely difficult, mainly because there is no single laboratory or radiological confirmatory test. Assessment of the clinical features and neurological signs, along with detection of antibodies in the serum and cerebrospinal fluid are necessary to arrive at a diagnosis. Lupus Cerebritis should be included in the provisional diagnosis of a female patient of reproductive age group, who presents with complicated neurological manifestations and with no clear-cut clinical, pathological, or image finding.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed4188    
    Printed110    
    Emailed5    
    PDF Downloaded561    
    Comments [Add]    
    Cited by others 1    

Recommend this journal