World Rural Health Conference
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 1272
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 1  |  Page : 63-68

Association of thyroid peroxidase antibody and dyslipidemia in subclinical hypothyroidism


Department of Family Medicine, Sri Balaji Action Medical Institute, New Delhi, India

Correspondence Address:
Vikas Kumar Srivastava
Department of Family Medicine, Sri Balaji Action Medical Institute, A4, Paschim Vihar, New Delhi - 110 063
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2249-4863.214958

Rights and Permissions

Context: Subclinical hypothyroidism (SCH) is stated as mild thyroid failure, is more common as compared to overt hypothyroidism, is associated with different biochemical abnormalities such as dyslipidemia, and is also having high conversion rate into overt hypothyroidism in patients having thyroid peroxidase (TPO) antibody positive. Lipid abnormalities are controversial in SCH and there is lack of Indian studies showing correlation between lipid abnormalities and TPO positivity in SCH. Hence, we did this study to find the TPO positivity and associated dyslipidemia in SCH patients. Materials and Methods: It was a prospective observational study from January 2015 to December 2015 including fifty adult diagnosed SCH patients presented in outpatient department of Sri Balaji Action Medical Institute, Paschim Vihar, New Delhi. TPO positivity and different lipid abnormalities were studied in those fifty diagnosed SCH patients, and finally, association between TPO antibody and dyslipidemia was calculated. Results: Females were predominant (86%). TPO was positive in 56% SCH patients. Dyslipidemia was found in 100% of SCH patients with positive TPO antibody. In overall, TPO positive patients as well as TPO positive females, total cholesterol, triglyceride, and low-density lipoprotein were significantly high while high-density lipoprotein was insignificant. In males, no significant association was found. Conclusion: In SCH patients, dyslipidemia is significantly associated with TPO positivity, especially in females. Hence, early screening, diagnosis, and treatment of SCH patients are recommended to prevent further risks.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed903    
    Printed10    
    Emailed0    
    PDF Downloaded161    
    Comments [Add]    
    Cited by others 1    

Recommend this journal