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CASE REPORT
Year : 2017  |  Volume : 6  |  Issue : 4  |  Page : 878-880

A case report of rapid-onset hyponatremia induced by low-dose olanzapine


1 Department of Psychiatry, Government Medical College, Thiruvananthapuram, Kerala, India
2 Department of Psychiatry, Dr. Kunhalu's Nursing Home, Ernakulam, Kerala, India
3 Department of Psychiatry, General Hospital, Ernakulam, Kerala, India

Correspondence Address:
Dr. Sethulakshmi Sreevalsam Anil
43/601, Thozhuthumparambil, Powathil Cross Road, Ayyappankavu, Ernakulam, Cochin - 682 018, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfmpc.jfmpc_205_17

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Hyponatremia has been reported with the use of psychotropic drugs. Olanzapine does not find much mention as a cause of hyponatremia in literature; however, it has been found to be the second most frequently reported atypical antipsychotic to cause it. We report a case of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion which occurred at a rapid onset following the administration of low-dose olanzapine during inpatient treatment of a patient with bipolar disorder. We would like to highlight our case for the need to be vigil about such fatal side complications apart from metabolic side effects of atypical antipsychotics.


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