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CASE REPORT
Year : 2018  |  Volume : 7  |  Issue : 1  |  Page : 267-270

Severe hypertriglyceridemia presenting as eruptive xanthomatosis


Department of Internal Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA

Correspondence Address:
Dr. Sameera S Vangara
University of Miami Miller School of Medicine, 1600 NW 10th Ave 1140, Miami, FL 33136
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfmpc.jfmpc_270_17

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Eruptive xanthomatosis is described as the sudden eruption of erythematous yellow papules in the presence of hypertriglyceridemia, often associated with serum triglyceride levels above 2000 mg/dl. Severe hypertriglyceridemia can be caused by primary genetic mutations, secondary chronic diseases, or a combination of both. Uncontrolled diabetes mellitus is a known risk factor. It is imperative for physicians to be aware of eruptive xanthomatosis as a warning sign for severe hypertriglyceridemia due to the underlying risk for the potentially fatal complication of acute pancreatitis. Herein, we discuss a case of a 52-year-old man with uncontrolled diabetes mellitus who presented with eruptive xanthomata and a triglyceride level of 7157 mg/dl, the highest recorded value in the absence of acute pancreatitis, with a remarkable response to drug therapy. A review of the literature is included to discuss the clinical relevance and appropriate treatment of this disease entity.


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