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CASE REPORT
Year : 2018  |  Volume : 7  |  Issue : 5  |  Page : 1109-1112

Pemphigus vulgaris – A report of three cases and review of literature


Department of Oral Medicine and Radiology, Haldia Institute of Dental Sciences and Research (HIDSAR), Balughata, Haldia, West Bengal, India

Correspondence Address:
Dr. Ishita Banerjee
Department of Oral Medicine and Radiology, Haldia Institute of Dental Sciences and Research (HIDSAR), Balughata- 721 645, Haldia, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfmpc.jfmpc_133_18

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Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule present on desmosomes. Histological features comprise intraepithelial cleft and Tzanck cells. Corticosteroids remain the mainstay of the treatment plan. In this article, we have discussed about the diagnosis of three patients suffering from PV, the treatment rendered, and the outcome of the same.


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