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 Table of Contents 
ORIGINAL ARTICLE
Year : 2019  |  Volume : 8  |  Issue : 1  |  Page : 148-153  

Biological risk factors for coronary artery disease among adults residing in rural area of North Karnataka, India


1 Department of Community Medicine, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi, Karnataka, India
2 Department of Internal Medicine, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi, Karnataka, India

Date of Web Publication31-Jan-2019

Correspondence Address:
Dr. Avinash Kavi
Department of Community Medicine, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi - 590 010, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfmpc.jfmpc_278_18

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  Abstract 


Background: Coronary artery disease (CAD) accounts for 60% of all deaths and 47% of burden of diseases which is progressively increasing in rural population in terms of absolute numbers. Biological risk factors contribute significantly to the cardiovascular burden. Hence, this study was undertaken to assess the biological risk factors among adults residing in rural area. Materials and Methods: A community-based cross-sectional study conducted among 980 adults aged between 20 and 60 years residing in rural area of Belagavi district, India. World Health Organization-STEPS-based predesigned questionnaire was used for data collection by house-to-house visit after obtaining written informed consent. Sociodemographic variables and biological risk factors which included hypertension, self-reported diabetes mellitus, overweight, and obesity were assessed. Statistical analysis was done using Pearson's Chi-square test and P value less than 0.05 was considered significant. Results: In the present study, 48.8% were men and 51.2% were women. Prevalence of hypertension was 26.6%, self-reported diabetes mellitus 6.3%, overweight 26.7%, and obesity was 7.0%. Men had higher prevalence of hypertension and overweight, whereas women had higher prevalence of diabetes and obesity. A significant gender difference was noted with the biological risk factors for CAD (P < 0.05). Advancing age, lesser education, and retirement from the job were the contributors for the increasing prevalence of these risk factors (P < 0.05); however, the socioeconomic status did not show any influence (P > 0.05). Conclusion: Biological risk factors, which included hypertension, diabetes, and overweight, were observed in a significantly higher proportion among men, whereas women were more obese with a significant higher proportion. Advancing age, lesser education, and retirement from the job were the contributors for the increasing prevalence of these risk factors.

Keywords: Adults, biological risk factors, coronary artery disease, North Karnataka, rural area


How to cite this article:
Kavi A, Walvekar PR, Patil RS. Biological risk factors for coronary artery disease among adults residing in rural area of North Karnataka, India. J Family Med Prim Care 2019;8:148-53

How to cite this URL:
Kavi A, Walvekar PR, Patil RS. Biological risk factors for coronary artery disease among adults residing in rural area of North Karnataka, India. J Family Med Prim Care [serial online] 2019 [cited 2019 Oct 15];8:148-53. Available from: http://www.jfmpc.com/text.asp?2019/8/1/148/251158




  Introduction Top


The globe is witnessing a rapid epidemiological transition. Infectious and nutritional diseases are receding among adults, whereas noncommunicable diseases are becoming increasingly common as the cause of morbidity and mortality.[1] In recent years, most of the developing countries including India are facing this challenge. Cardiovascular diseases (CVDs), which include coronary artery disease (CAD), are responsible for 60% of all deaths and 47% of burden of diseases.[2] As per the World Health Report – 2002, CVDs will be the largest cause of death and disability in India by 2020.[3] It has been estimated that 2% reduction in chronic diseases' death rates per year globally could result in saving about 36 million premature deaths by the year 2015.[4] The CAD has assumed the “epidemic” proportion in India and many other developing countries. The prevalence rates can be estimated from several studies over the past several decades which have ranged from 1.6% to 7.4% in rural population and 1% to 13.2% in urban population.[5] Though the disease is more prevalent in urban population, it is progressively increasing in rural population in terms of absolute numbers.[6]

The majority of the individuals who develop heart attacks and strokes every year have one or more cardiovascular risk factors. Most of these cardiovascular events are preventable if meaningful action is taken against the risk factors.[7] Early detection of CAD risk factors and appropriate intervention reduces the mortality by 35–60%.[8] Major biological coronary risk factors – high blood pressure, overweight, obesity, and diabetes – are found to be escalating in rural population and correlate positively with the increase in CAD.[8]

The basis of CAD prevention is the identification of the major common risk factors and their prevention and control. The risk factors of today are the diseases of tomorrow.[9] Thus, there is a felt need to establish CAD risk factors surveillance in a country, especially in the rural area. The primary care family physicians play a pivotal role in health-care delivery in the rural area and risk assessment will enable for a tangible action for CAD control. Once we have such data, interventions can be planned and implemented at primary care level to minimize biological risk factors, thereby minimizing the health risks of increasing CAD-related mortality and morbidity. Thus, a community-based study to assess the biological risk factors for CAD among adults residing in rural area was conducted.


  Materials and Methods Top


The community-based cross-sectional study conducted from January 2013 to June 2015 among adults aged between 20 and 60 years residing in the villages of Kakati subcenter under Primary Health Centre, Vantamuri, Belagavi District, Karnataka, India. The study was approved by the Institutional Ethics Committee for Human Subject's Research, Jawaharlal Nehru Medical College, Belagavi. The sample size (N) was calculated using the formula N = 4pq/d2, where P is the prevalence of overweight as 11%[10] and d is the absolute error as 2%; the sample size obtained was 980. Sampling frame of the adult residents of the villages was prepared using the recent voter's list and participants were included in study by simple random sampling technique using standard random number table.

Written informed consent was obtained from every participant. A pilot study was conducted and necessary modifications were made as per the local requirements. Data were collected by visiting the selected houses using a predesigned questionnaire based on World Health Organization (WHO)-STEPS Surveillance Manual,[9] which included personal and sociodemographic variables, namely, age, gender, education, main work status, and socioeconomic status (SES) classified as per the modified BG Prasad Classification. The biological risk factors assessment included raised blood pressure, history of diabetes mellitus, overweight, and obesity.[9]

Self-reported history of diabetes was assessed either by documentation by physician or if the person is on oral hypoglycemic agents or insulin or both.[11] During the course of interview, three measurements of blood pressure of each study participant were measured using mercury sphygmomanometer at an interval of 5 min in sitting position. The average of last two SBP and DBP reading in mmHg was noted to describe the blood pressure of the participant.[5] Study participants were classified as “normotensive,” “prehypertensive,” or “hypertensive (grade I and II)” on the basis of their blood pressure levels according to JNC VII criteria.[12]

Body weight was measured without any foot wear and with minimal clothing to the nearest 0.1 kg using a standard portable adult weighing machine, which was standardized periodically during the study.[6] As per the revised guidelines recommended by WHO, persons with BMI values of less than 18.5 were classified as “underweight,” 18.5–24.99 were classified as “normal weight,” 25.0–29.99 were classified as “overweight/preobese,” and 30.0 and above were classified as “obese.”[13] Waist circumference (WC) >80 cm for women and >90 cm for men was considered to have abdominal obesity.[14] The ratio of waist-to-hip circumference (WHR) >0.85 in women and >1.0 in men was considered to have abdominal obesity.[15]

Data were expressed in percentages and were entered in the excel spreadsheet using numerical codes. Analysis was performed using Statistical Package for Social Sciences, version 20.0. Mean ± standard deviation was derived for the continuous variables. Categorical data analysis was done using Pearson's Chi-square test and probability value (P value) of less than 0.05 was considered as statistically significant.


  Results Top


Among the 980 participants of the study, 478 (48.8%) were men with mean age 38.2 ± 10.66 years and 502 (51.2%) were women with mean age 40.4 ± 11.32 years. In our study, 23.9% participants were between age group of 20–29 years, 25.5% between 30 and 39 years, 26.7% between 40 and 49 years, and 23.9% were more than or equal to 50 years. When we assessed their main work status, 6.6% of the participants were government employees, 12.1% were nongovernment employees, 38.6% were self-employed, 36.2% were homemakers, 2.2% were students, 1.7% were retired, and 2.6% were unemployed. Regarding highest level of education, 28.5% did not have any formal education, 14% studied up to primary school level, 13.7% up to higher primary level, 28.8% up to high school level, and 15.1% above high school level. Majority of study participants, 37.6%, belonged to class IV SES as per modified BG Prasad Classification, followed by 30.1% in class III, 15.6% in class II, 13.5% in class V, and least in class I, that is, 3.2%.

The prevalence of hypertension was 26.6%, grade I and grade II being 19.7% and 6.9%, respectively. Hypertension prevalence was slightly higher in males (27.8%) as compared to females (25.5%) and was statistically significant (P = 0.004). However, the prevalence of self-reported hypertension (who were diagnosed prior and/or on antihypertensives) in our study was 20.2%. The prevalence among women was higher (22.9%) compared to men (17.4%) (P = 0.031). Prevalence of self-reported history of diabetes mellitus was 6.3%. Men had higher prevalence (7.9%) as compared to women (4.8%) (P = 0.042). The overall prevalence of overweight and obesity were 26.7% and 7.0%, respectively, as per the BMI criteria. The proportion of overweight was higher among men compared to women (31.8% vs. 21.7%), whereas among obese, women outnumbered men (10.3% vs. 3.5%). This difference was statistically significant (P < 0.0001). The prevalence of abdominal obesity assessed using WC criteria was 37.9%, and based on waist: hip ratio, criterion was 69.2%. The proportion among women was double than that of men (P < 0.0001) [Table 1].
Table 1: Gender-wise distribution of the participants according to various categories of biological risk factors (n=980)

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The proportion of hypertensives, diabetics, overweight, and obese individuals increased as age advanced and maximum prevalence was in ≥50 years group with statistical association (P < 0.0001) [Table 2].
Table 2: Association between age groups and biological risk factors for CAD (n=980)

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The prevalence of hypertension was significantly high (39.1%) among participants without any formal education and the prevalence decreased with higher education levels (P < 0.001). Self-reported diabetes prevalence was high in participants with education of primary level or less (P < 0.020). Overweight and obesity assessed by BMI categories did not differ with education level (P = 0.096). However, lesser or no formal education contributed to the higher proportion of abdominal obesity assessed by WC and WHR categories (P < 0.0001) [Table 3].
Table 3: Association between educational status and biological risk factors for CAD (n=980)

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Retired personnel had highest proportion of diabetes (29.4%), hypertension (35.5%), and overweight (35.3%) as compared to the other work status. Homemakers had higher proportion of abdominal obesity (P < 0.0001). However, the hypertension did not vary significantly across different work status (P = 0.218). Additionally, any of the biological risk factors assessed in this study did not differ significantly among different SES of the participants (P > 0.05) [Table 4].
Table 4: Association between main work status and biological risk factors for CAD (n=980)

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  Discussion Top


This study assessed various biological risk factors for CAD among the adult residents in the rural area. The higher women participants in this study (51.2% vs. 48.8%) were comparable with two studies conducted in rural area of Faridabad and Delhi districts of North India, where the proportion of women was higher (52.0%; 62.5%) as compared to men (48.0%; 37.5%), respectively.[16],[17]

The prevalence of hypertension was among 26.6% of the participants, with higher prevalence among men. A study conducted at rural area of Indonesia and Nepal reported a similar overall prevalence of 21.6% and 26.0%, respectively.[18],[19] A study done in rural area of Pune district also substantiated our findings of higher proportion of hypertension among men (19.7%) compared to women (15.6%).[20] Three other studies reported overall higher prevalence of hypertension of 36.9%, 35.3%, and 36% done at New Delhi, Eastern Nepal, and Bhutan, respectively.[17],[21],[22] Self-reported hypertension was much lower (20.2%) as compared to a study done in the rural area of Mukim Dengkil, Malaysia (31.7%).[23] A similar study done at rural Faridabad district showed a higher prevalence of self-reported hypertension among women (6.8%) compared to men (3.5%).[16] In our study, 6.3% of them reported having diabetes mellitus, with higher proportion among men (7.9%) than women (4.8%). Study conducted at rural area of Tamil Nadu reported a lower prevalence of 4.0%.[24] Another study done in 18 states of India documented a higher prevalence among women (4.4%) than men (3.3%).[25] A study conducted in the rural area of Nigeria reported prevalence of 8.0%, of which 6.1% was self-reported which was consistent with our study.[26]

The overall prevalence of overweight and obesity assessed by BMI categories was 26.7% and 7.0%, respectively. Study conducted in rural area of Pune reported 18.0% of overweight and 3.2% of obesity which was much less compared to our study.[20] Study conducted among adults of rural Nepal reported a composite prevalence of BMI ≥25 kg/m 2 as 21%.[19] The prevalence of obesity among women was high compared to men. Similar findings were documented in a study done in other rural areas of Mukim Dengkil, Malaysia, and Tamil Nadu, India.[23],[24] Overall, 33.7% of the participants had BMI >25.0 in our study which was well in accordance with the estimated range of overall prevalence for Southeast Asia, that is, 26.3–56.0%.[27] Abdominal obesity assessed by WC and WHR showed higher proportion, 37.9% and 69.2%, respectively, with significantly higher proportion among women. Other similar studies documented a lesser over all prevalence, but the proportion was higher among women.[17],[20],[24],[25],[28] The remarkable high WHR and WC (measure of abdominal obesity) observed in our study in both men (41.0% and 23.0%, respectively) and women (96.0% and 52.0%, respectively) require special attention. A study conducted in semi-rural population of the community of Gueoul in Senegal reported the prevalence of abdominal obesity as 53.9% and global obesity as 13%.[29]

Similar finding with twofold increased prevalence among women was observed in a study done in rural area of Thiruvananthapuram district, Kerala.[30] Increased predisposition to premature CAD in Indians has been attributed to the “Asian Indian phenotype,” characterized by less of generalized obesity measured by BMI and greater central body obesity as shown by greater WC and WHR.[31] Our study substantiates this hypothesis.

In our study, the association of various biological risk factors with age was statistically significant for hypertension, self-reported DM, overweight and obesity, and WC and WHR categories. The proportion of the risk factors increased with the advancing age. Similar findings were reported by other studies conducted in rural areas of Nigeria, Eastern Nepal, Malaysia, Vietnam, Indonesia, Tamil Nadu, Maharashtra, and Northern India.[18],[20],[21],[23],[24],[32],[33],[34] There was a higher prevalence of hypertension at older ages, among females (8.2%) compared to males (7.7%) in a study conducted in the rural areas of North West Tanzania.[35]

An inverse-graded relationship of various risk factors and educational status was observed for hypertension, self-reported DM, abnormal WC, and WHR categories where the prevalence decreased with increased education levels. Prevalence of overweight and obesity did not differ statistically with education, though the lowest prevalence was among highest level of education (P = 0.09). Similar finding was noted in a multicenter community-based studies conducted in India.[36],[37] This assessment at primary care level is necessary to stratify the persons with risk factors and decide the accessibility and affordability so that effective strategies can be implemented.

The association of various risk factors with main work status was statistically significant for – self-reported DM, overweight, obesity, and abnormal WC and WHR categories. Prevalence of hypertension did not show statistical difference between work categories. Retired individuals had highest prevalence of self-reported DM and overweight. Government employees were more obese. Homemakers who were predominantly women were having highest prevalence of central obesity. Similar findings were noted in a study conducted in rural Vietnam.[33] In our study, SES did not show any association with biological risk factors. Self-reported DM, high blood pressure, and abdominal obesity did not differ in their prevalence across the SES class. A similar finding was observed in a multicenter study conducted in 18 states of India and rural Vietnam.[25],[33] The risk factor assessment at the primary care level in the rural area will help the policy makers in formulating need-based programs which can be effectively implemented.

Limitations

This study did not address the behavioral and biochemical risk factors for CAD though they formed an important part of the risk assessment. The prevalence of diabetes mellitus was not measured by blood glucose assessment due to the constraint of resources and lack of feasibility.

Implications

Residents of the rural area lack the necessary health-care infrastructure and management facilities for CAD due to variety of constraints, including the low SES and lack of education. Thus, aiming at the primary prevention by assessment of the modifiable biological risk factors and doing selective screening instead of universal screening and targeted interventions can be undertaken to minimize the risk factors and hence combat the problem of increasing CAD-related mortality and morbidity in the economically disadvantaged group of the society. Risk assessment by primary care physicians can aid in planning the appropriate interventions suiting to the local needs.


  Conclusion Top


Biological risk factors, which included hypertension, diabetes, and overweight, were observed in a significantly higher proportion among men, whereas women were more obese with a significant higher proportion. Advancing age, lesser education, and retirement from the job were the contributors for the increasing prevalence of these risk factors; however, the SES did not show any influence on the risk factors. Our study demonstrated a significant higher prevalence of biological risk factors for CAD in rural population in South India. Burden of CAD risk factors in this population reflects the epidemiological transition which requires an immediate attention.

Acknowledgments

The authors regard and condolence to Late Mr. M. D. Mallapur, Asst. Professor of Biostatistics, who carried out the statistical analysis for this study. They also sincerely thank to the Medical Officers of PHC, Vantamuri, and the staff of the Kakati subcenter for their cooperation and support in data collection; Dr. Vijaya A. Naik, and Dr. S. M. Katti, the former heads of the department for their able guidance in conduct of the study.

Author contributions

AK developed the protocol, conceptualized the project design, analyzed and interpreted the data, and drafted the article; PRW developed the idea, supervised and monitored all aspects of this study, and assisted in analysis and revised the manuscript critically for important intellectual content; RSP provided the necessary technical support as subject expert with clinical assistance. All authors have read and approved the final draft of the manuscript.

Ethical approval

Ethical clearance was obtained from the Institutional Ethics Committee of J. N. Medical College, KLE Academy of Higher Education and Research, Belagavi. All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed written/thumb print consent was obtained from all respondents after a full explanation of the nature, purpose and procedures used for the study.

Financial support and sponsorship

This was a self-funded study.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Reddy KS. Cardiovascular diseases in the developing countries: Dimensions, determinants, dynamics and directions for public health action. Public Health Nutr 2002;5:231-7.  Back to cited text no. 1
    
2.
The Global Burden of Disease. 2004 Update. World Health Organization, 2008. Available from: http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_full.pdf. [Last accessed on 2017 May 01].  Back to cited text no. 2
    
3.
The World Health Report 2002-Reducing Risks, Promoting Healthy Life. Geneva, Switzerland: World Health Organization, 2002. Available from: http://www.who.int/whr/2002/en/n. [Last accessed on 2017 Aug 22].  Back to cited text no. 3
    
4.
Preventing chronic disease: A vital investment. Geneva; World Health Organization; 2005.  Back to cited text no. 4
    
5.
Prevention of cardiovascular disease: Guidelines for assessment and management of total cardiovascular risk. Geneva, Switzerland, World Health Organization; 2007. Available from: http://www.who.int/CHD/risk_factor assessment. [Last accessed on 2018 May 14].  Back to cited text no. 5
    
6.
Gupta R, Rastogi P, Deepali H, Mathur B, Bharadwaj AK. Coronary heart disease and risk factors in rural population of India. South Asian J Prevent Cardiol 2003;7:4.  Back to cited text no. 6
    
7.
WHO CVD – Risk management package for low and medium-resource settings. Geneva, Switzerland, World Health Organization, 2002.  Back to cited text no. 7
    
8.
Wayne Taylor D. The Burden of Non-Communicable Diseases in India, Hamilton ON: The Cameron Institute; 2010.  Back to cited text no. 8
    
9.
WHO STEPS Surveillance Manual. Geneva, Switzerland, World Health Organization; 2008. Available from: http://www.who.int/NCD/STEPS Approach. [Last accessed on 2017 Jan 17].  Back to cited text no. 9
    
10.
National Family Health Survey (NFHS – 3), 2005 –2006: India: Volume I. Mumbai: IIPS.  Back to cited text no. 10
    
11.
Non-communicable Diseases Country Profiles. Geneva, Switzerland, World Health Organization, 2011. Available from URL: http://whqlibdoc.who.int/publications/2011/9789241502283_eng.pdf. [Last accessed on 2018 Apr 25].  Back to cited text no. 11
    
12.
Chobanian AV. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: The JNC 7 report. J Am Med Assoc 2003;289:2560-72.  Back to cited text no. 12
    
13.
Park K. Park's Textbook of Preventive and Social Medicine. 22th ed. Jabalpur, India: Banarasidas Bhanot; 2013.  Back to cited text no. 13
    
14.
WHO Expert Consultation Group. Appropriate body mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;364:157-63.  Back to cited text no. 14
    
15.
Obesity: Preventing and managing the global epidemic. Report of a WHO consultation on Obesity. Geneva, World Health Organization; 1998.  Back to cited text no. 15
    
16.
Krishnan A, Shah B, Lal V, Shukla DK, Paul E, Kapoor SK. Prevalence of risk factors for non communicable disease in a rural area of faridabad district of Haryana. Indian J Public Health 2008;52:117-24.  Back to cited text no. 16
[PUBMED]  [Full text]  
17.
Laskar A, Sharma N, Bhagat N. Lifestyle disease risk factors in a North Indian community in Delhi. Indian J Community Med 2010;35:426-8.  Back to cited text no. 17
[PUBMED]  [Full text]  
18.
Nawi N, Stenlund H, Bonita R, Hakimi M, Wall S, Weinehall L. Preventable risk factors for non-communicable diseases in rural Indonesia: Prevalence study using WHO STEPS approach. Bull World Health Organ 2006;84:305-13.  Back to cited text no. 18
    
19.
Aryal KK, Mehata S, Neupane S, Vaidya A, Dhimal M, Dhakal P, et al. The Burden and determinants of non communicable diseases risk factors in Nepal: Findings from a Nationwide STEPS Survey. PLoS One 2015;10:e0134834.  Back to cited text no. 19
    
20.
Agarwal VK, Basannar DR, Sing RP, Dutt M, Abraham D, Mustafa MS. Coronary risk factors in a rural community. Indian J Public Health 2006;50:19-23.  Back to cited text no. 20
    
21.
Kalra S, Narain S, Karki P, Ansari JA, Ranabhat K, Basnet N. Prevalence of risk factors for coronary artery disease in the community in Eastern Nepal – A pilot study. JAPI 2001;59:300-1.  Back to cited text no. 21
    
22.
Pelzom D, Isaakidis P, Oo MM, Gurung MS, Yangchen P. Alarming prevalence and clustering of modifiable noncommunicable disease risk factors among adults in Bhutan: A nationwide cross-sectional community survey. BMC Public Health 2017;17:975.  Back to cited text no. 22
    
23.
Yunus AM, Sherina MS, Nor Afiah MZ, Rampal, Tiew KH. Prevalence of cardiovascular risk factors in a rural community in Mukim Dengkil, Selangor. Malays J Nutr 2004;10:5-11.  Back to cited text no. 23
    
24.
Kaur P, Rao SR, Radhakrishnan E, Ramachandran R, Venkatachalam R, Gupte MD. High prevalence of tobacco use, alcohol use and overweight in rural population in Tamil Nadu, India. J Postgrad Med 2011;57:9-15.  Back to cited text no. 24
[PUBMED]  [Full text]  
25.
Kinra S, Bowen LJ, Lyngdoh T, Prabhakaran D, Reddy KS, Ramakrishnan L, et al. Socio-demographic patterning of non-communicable disease risk factors in rural India: A cross sectional study. BMJ 2010;341:c4974-82.  Back to cited text no. 25
    
26.
Arugu GM, Maduka O. Risk factors for diabetes mellitus among adult residents of a rural District in Southern Nigeria: Implications for prevention and control. Niger J Clin Pract 2017;20:1544-9.  Back to cited text no. 26
[PUBMED]  [Full text]  
27.
Philip W, James T, Rachel. Overweight and obesity (high body mass index). In: Ezzati M, Lopez AD, Rodgers A, editors. Comparative Quantifications of Health Risks. 1st ed. Geneva, WHO; 2004. p. 497-597.  Back to cited text no. 27
    
28.
Maimela E, Alberts M, Modjadji SE, Choma SS, Dikotope SA, Ntuli TS, et al. The Prevalence and determinants of chronic non-communicable disease risk factors amongst adults in the Dikgale health demographic and surveillance system (HDSS) Site, Limpopo Province of South Africa. PLoS One 2016;11:e0147926.  Back to cited text no. 28
    
29.
Mbaye A, Babaka K, Ngaïde AA, Gazal M, Faye M, Niang K, et al. Prevalence of cardiovascular risk factors in semi-rural area in Senegal. Ann Cardiol Angeiol (Paris) 2018;67:264-9.  Back to cited text no. 29
    
30.
Thankappan KR, Shah B, Mathur P, Sarma PS, Srinivas G, Mini GK, et al. Risk factor profile for chronic non-communicable diseases: Results of a community based study in Kerala, India. Indian J Med Res 2010;131:53-63.  Back to cited text no. 30
[PUBMED]  [Full text]  
31.
Yagnik CS, Ganpule Rao AV. The obesity – diabetes association: What is different in Indians? Int J Low Extrem Wounds 2010;9:113-5.  Back to cited text no. 31
    
32.
Ejim EC, Okafor CI, Emehel A, Mbah AU, Onyia U, Egwuonwu T, et al. Prevalence of cardiovascular risk factors in the middle-aged and elderly population of a Nigerian rural community. J Tropical Med 2011.  Back to cited text no. 32
    
33.
Pham LH, Thuy BA, Blizzard L, Truong NB, Schmidt MD, Granger RH, et al. Prevalence of risk factors for non-communicable diseases in the Mekong Delta, Vietnam: Results from a STEPS survey. BMC Public Health 2009;9:291-8.  Back to cited text no. 33
    
34.
Gupta R, Mishra A, Naval VK, Kondal D, Gupta SS, Agarwal A, et al. Younger age escalation of cardio vascular risk factors in Asian Indians. BMC Cardiovasc Disord 2009;9:28-34.  Back to cited text no. 34
    
35.
Mosha NR, Mahande M, Juma A, Mboya I, Peck R, Urassa M, et al. Prevalence, awareness and factors associated with hypertension in North West Tanzania. Glob Health Action 2017;10:1321279.  Back to cited text no. 35
    
36.
Gupta R, Gupta VP, Ahluwalia NS. Educational status, coronary heart disease, and coronary risk factor prevalence in a rural population of India. BMJ 1994;309:1332-41.  Back to cited text no. 36
    
37.
Reddy KS, Prabhakaran D, Jeemon P, Thankappan KR, Joshi P, Chaturvedi V, et al. Educational status and cardiovascular risk profile in Indians. Proc Natl Acad Sci USA 2007;104:16263-8.  Back to cited text no. 37
    



 
 
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  [Table 1], [Table 2], [Table 3], [Table 4]



 

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