Journal of Family Medicine and Primary Care

CASE REPORT
Year
: 2016  |  Volume : 5  |  Issue : 4  |  Page : 875--878

Low-dose methotrexate-induced acute interstitial pneumonitis: Report of two cases from South India and review of literature


Ramya Iyyadurai, Ronald Albert Benton Carey, Sowmya Satyendra 
 Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Ramya Iyyadurai
Department of Medicine, Christian Medical College, Vellore  -  632  004, Tamil  Nadu
India

Methotrexate (MTX) is an antimetabolite used as a disease-modifying agent for various rheumatological conditions. We report two patients who were treated with daily low-dose MTX and developed acute interstitial pneumonitis requiring hospital admission. MTX-induced pneumonitis is a rare life-threatening side effect, high index of clinical suspicion is required, treatment is mainly withdrawal of MTX, supportive therapy, and adjunctive steroids, outcome is good if condition is recognized early, and appropriate treatment is given.


How to cite this article:
Iyyadurai R, Carey RA, Satyendra S. Low-dose methotrexate-induced acute interstitial pneumonitis: Report of two cases from South India and review of literature.J Family Med Prim Care 2016;5:875-878


How to cite this URL:
Iyyadurai R, Carey RA, Satyendra S. Low-dose methotrexate-induced acute interstitial pneumonitis: Report of two cases from South India and review of literature. J Family Med Prim Care [serial online] 2016 [cited 2019 Sep 15 ];5:875-878
Available from: http://www.jfmpc.com/article.asp?issn=2249-4863;year=2016;volume=5;issue=4;spage=875;epage=878;aulast=Iyyadurai;type=0