Journal of Family Medicine and Primary Care

REVIEW ARTICLE
Year
: 2019  |  Volume : 8  |  Issue : 5  |  Page : 1533--1539

Cytochemical tests to investigate sperm DNA damage: Assessment and review


Soheila Pourmasumi1, Alireza Nazari1, Niloofar Fagheirelahee2, Parvin Sabeti3 
1 Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
2 Student Research Committee, Iran University of Medical Sciences, Tehran, Iran
3 Department of Anatomy, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran

Correspondence Address:
Dr. Parvin Sabeti
Department of Anatomy, Faculty of Medicine, Kurdistan University of Medical Sciences, Pasdaran Street, Sanandaj
Iran

Male factor infertility has been diagnosed as the cause of infertility in about 20% of infertile couples. Sperm analysis is the most common method for diagnosing infertility in a laboratory. However, approximately 15% of infertile men have a normal sperm analysis. Therefore, the result of a routine sperm analysis often cannot be a definitive diagnosis for male factor infertility. Also, approximately 8% of infertile men with normal sperm parameters have high levels of abnormal sperm DNA. This indicates the role of the integrity of sperm DNA in male infertility. Here, we review the current tests available to evaluate the sperm DNA integrity along with their benefits and limitations.


How to cite this article:
Pourmasumi S, Nazari A, Fagheirelahee N, Sabeti P. Cytochemical tests to investigate sperm DNA damage: Assessment and review.J Family Med Prim Care 2019;8:1533-1539


How to cite this URL:
Pourmasumi S, Nazari A, Fagheirelahee N, Sabeti P. Cytochemical tests to investigate sperm DNA damage: Assessment and review. J Family Med Prim Care [serial online] 2019 [cited 2019 Oct 22 ];8:1533-1539
Available from: http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=5;spage=1533;epage=1539;aulast=Pourmasumi;type=0