| CASE REPORT |
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| Year : 2014 | Volume
: 3
| Issue : 4 | Page : 456-457 |
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Noncardiac pulmonary edema induced by sitagliptin treatment
Tahir Belice1, Suleyman Yuce1, Bayram Kizilkaya1, Aysel Kurt2, Erkan Cure1
1 Department of Internal Medicine, School of Medicine, Recep Tayyip Erdogan University, Islampasa Mahallesi, Rize, Turkey
2 Department of Thoracic Surgery, Recep Tayyip Erdogan University, Islampasa Mahallesi, Rize, Turkey
Correspondence Address:
Erkan Cure
Department of Internal Medicine, School of Medicine, Recep Tayyip Erdogan University, Islampasa Mahallesi, Rize 53100
Turkey
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2249-4863.148149
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A 74-year-old male patient with type 2 diabetes mellitus admitted to the emergency department with the complaints of progressive breathlessness, dry cough, and swollen lower extremities. Our patient had type 2 diabetes mellitus and hypertension for 3 years. His HbA1c was not within the target range so sitagliptin was added to on-going therapy. After 1 week of starting sitagliptin therapy, even though the patient had not heart failure he applied to the emergency department with a complaint of dyspnea. The cardiovascular safety and efficacy of many anti-hyperglycemic agents such as sitagliptin, saxagliptin are unclear. Our case has shown that dipeptidyl peptidase 4 inhibitors may cause pulmonary edema. Hence, it should be used with cautious, especially in patients with heart failure. |
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