| CASE REPORT |
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| Year : 2018 | Volume
: 7
| Issue : 1 | Page : 271-273 |
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Splenic granuloma: Melioidosis or Tuberculosis?
Fibi Ninan, Ajay Kumar Mishra, Ajoy Oommen John, Ramya Iyadurai
Department of General Medicine, Christian Medical College, Vellore, Tamil Nadu, India
Correspondence Address:
Dr. Fibi Ninan
Department of General Medicine, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jfmpc.jfmpc_171_17
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Melioidosis well known as a 'great mimicker' is caused by Burkholderia pseudomallei. Even though majority of the patients present with acute infection, around 18 % can present as chronic infection. These latent foci of infection may reactivate to cause fulminant infection at a later date. Due to lack of clinical suspicion and good laboratory facility latent infections are often misdiagnosed and treated as tuberculosis. Chronic splenic granuloma is a rare manifestation of Melioidosis . Deep seated abscess requires atleast 4 weeks of intensive treatment with intravenous antibiotics. Ceftazidime , the drug of choice for melioidosis can cause drug induced thrombocytopenia. Simultaneous use of diclofenac may potentiate this phenomenon. Treatment with meropenem may be life saving in such situitations.
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