Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 5132
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2018  |  Volume : 7  |  Issue : 6  |  Page : 1279-1282

Estimation of serum prolactin levels and determination of prevalence of hyperprolactinemia in newly diagnosed cases of subclinical hypothyroidism

1 DNB Family Medicine, SBAMI, New Delhi, India
2 Department of Medicine, SBAMI, New Delhi, India

Correspondence Address:
Dr. Tanvi Sirohi
A-2/311, Sunrise Apartments, Rohini (Sec-13), Delhi - 110 085
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jfmpc.jfmpc_155_18

Rights and Permissions

Background: Hyperprolactinemia is a common endocrine disorder involving hypothalamic–pituitary axis. Prolactin (PRL) secretion is stimulated by dopamine antagonism and thyroid-releasing hormone. Hyperprolactinemia has been reported in subclinical hypothyroidism (SCH) but results are markedly variable and studies on SCH are very few. The objective of this study was to find out prevalence of hyperprolactinema in newly diagnosed subclinical hypothyroid patients. Materials and Methods: In this cross-sectional study, serum PRL levels of 150 newly diagnosed subclinical hypothyroid patients were determined using electrochemiluminescence method. Results: Raised PRL levels were found in 18 (%) patients with SCH. There was positive correlation between serum thyroid-stimulating hormone and PRL levels. Prevalence of infertility was significantly higher with presence of hyperprolactinemia than normoprolactinemia in subclinical hypothyroid patients. Conclusion: Routine prolactin estimation and subsequent treatment is required in patients with subclinical hypothroidism.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded209    
    Comments [Add]    
    Cited by others 2    

Recommend this journal