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Year : 2020  |  Volume : 9  |  Issue : 5  |  Page : 2469-2474

The study of placentrex and hydrocortisone as an adjunct treatment in oral submucous fibrosis

1 Consultant Oral and Maxillofacial Surgeon, Mangalmurti Multi Speciality Dental Clinic, Natepute, Maharashtra, India
2 Conservative Dentistry and Endodontics, Government Dental Surgeon, PHC Sampatchak, Patna, Bihar, India
3 Consultant Oral and Maxillofacial Surgeon, Smilecraft Dental Studio, Yelahanka New Town, Banglore, Karnataka, India
4 Intern, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India
5 Consultant Oral and Maxillofacial Surgeon, Jyoti Kendra General Hospital, Ludhiana, Punjab, India
6 Departments of Oral and Maxillofacial Surgery, Dr. H.S.R.S.M Dental College and Hospital, Hingoli, Maharashtra, India
7 Consultant Oral and Maxillofacial Surgeon, Clove Dental and Omni Hospitals, Visakhapatnam, Andhra Pradesh, India

Correspondence Address:
Dr. Vijay Shekhar
Conservative Dentistry and Endodontics, Government Dental Surgeon, PHC Sampatchak, Patna . 800 007, Bihar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jfmpc.jfmpc_268_20

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Background: Submucous fibrosis with a high incidence rate in the Indian subcontinent is a devastating disease affecting the oral cavity and oropharynx. Aims and Objective: To evaluate the efficacy of injection placentrex and injection hydrocortisone in oral submucous fibrosis patients in increasing mouth opening, burning sensation, and improve the mucosal lining. Materials and Methods: We recruited 60 patients with Stage II and Stage III of the ailment, who were randomly divided into Group A and Group B. They were administered submucosal injections of hydrocortisone and placentrex along with physiotherapy and oral iron, nutrients, and B-carotene supplements over a period of 2 months. Interpretations and Results: The pinnacle rate of the incidence was found in the age group of 30 to 40 years among both the genders. Statistically significant difference (P = 0.0001), that is, 5.19 ± 1.33 in Group A and 11.69 ± 1.26 mm in Group B was noted in the mean mouth opening values. Statistically significant difference in burning sensation was noted to be better in Group A than in Group B. Discussion and Conclusion: Overall hydrocortisone seems to be a better regimen for improving the mucosal health and increasing the mouth opening as compared to placentrix regimen. Although Placentrex is better than hydrocortisone in reducing burning sensation.

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