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Year : 2020  |  Volume : 9  |  Issue : 7  |  Page : 3762-3765

The great masquerader: Hemophagocytic lymphohistiocytosis secondary to cytomegalovirus infection in an immunocompetent young man

Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India

Correspondence Address:
Dr. Ajay Chauhan
Professor of Medicine, R. No 104, Academic Block, Post Graduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, Ministry of Health and Family Welfare, Govt. of India, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jfmpc.jfmpc_274_20

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Hemophagocytic lymphohistiocytosis (HLH) is a rare, poorly recognized and underdiagnosed syndrome of excessive immune activation, which is rapidly fatal. HLH can occur as a familial or secondary disorder. Secondary HLH is most commonly associated with infections, malignancies, or autoimmune diseases. It primarily affects patients with a compromised immune system and rarely presents in immunocompetent individuals. Acute cytomegalovirus (CMV) associated HLH in the immunocompetent individual is extremely rare and only documented in five case reports till date. We, hereby, report a case of 18 years old young immunocompetent man who was diagnosed to have HLH secondary to CMV infection.

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