Journal of Family Medicine and Primary Care

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 9  |  Issue : 6  |  Page : 2877--2879

The role of oral vitamin D3 supplementation in the treatment of Chronic Rhinosinusitis in adults with Vitamin D deficiency


Binayak Baruah, Ajay Gupta, Abhijit Kumar, Alok Kumar 
 Department of ENT, Tata Main Hospital, Jamshedpur, Jharkhand, India

Correspondence Address:
Dr. Binayak Baruah
Consultant, Department of ENT, Tata Main Hospital, Bistupur, Jamshedpur - 831 001, Jharkhand
India

Background: Chronic Rhinosinusitis (CRS) is a chronic inflammatory disorder of the mucosal lining of the nose and paranasal sinuses. The ability of Vitamin D (VD3) to augment innate and adaptive immune responses has sparked interest in its immunologic role in the treatment of CRS. In this study, the incidence of vitamin D deficiency in CRS patients was compared to normal population and the beneficial role of Vitamin D supplementation in its treatment was also evaluated. Materials and Methods: It is a retrospective 1-year study of 200 CRS patients with Vitamin D deficiency. The patients were divided into two groups, i.e. 100 patients were given oral Vitamin D supplements and the other group of 100 patients were treated as placebo. Both Vitamin D levels and the Total Nasal Symptom Score (TNSS) were assessed at the start and end of the study period. Results: Of the 200 subjects with CRS, 100 were given oral vitamin D supplementation in the form of Cholecalciferol 60000IU weekly once for 3 months and the other group were treated with placebo. Before the treatment, the average level of serum Vitamin D was 12.31 ng/ml. After 3 months, it increased significantly to 29.71 ng/ml. Similarly, the pretreatment TNSS score was on average 11.92. After 3 months, the scores fell by an average of 10.65 points, a significant statistical difference (P < 0.05). Conclusion: There is a higher prevalence of vitamin D deficiency in CRS patients and that vitamin D supplementation in these patients went a long way in alleviating their symptoms.


How to cite this article:
Baruah B, Gupta A, Kumar A, Kumar A. The role of oral vitamin D3 supplementation in the treatment of Chronic Rhinosinusitis in adults with Vitamin D deficiency.J Family Med Prim Care 2020;9:2877-2879


How to cite this URL:
Baruah B, Gupta A, Kumar A, Kumar A. The role of oral vitamin D3 supplementation in the treatment of Chronic Rhinosinusitis in adults with Vitamin D deficiency. J Family Med Prim Care [serial online] 2020 [cited 2020 Oct 28 ];9:2877-2879
Available from: https://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=6;spage=2877;epage=2879;aulast=Baruah;type=0