Journal of Family Medicine and Primary Care

CASE REPORT
Year
: 2020  |  Volume : 9  |  Issue : 7  |  Page : 3766--3769

Epistaxis presenting as sentinel feature of metastatic renal cell carcinoma: A case report and review of literature


Satish K Ranjan, Ankur Mittal, Sunil Kumar, Kim J Mammen, Shiv C Navariya, Deepak P Bhirud 
 Department of Urology, AIIMS, Rishikesh, Uttarakhand, India

Correspondence Address:
Dr. Sunil Kumar
Department of Urology, 6th Level, Medical College Building, AIIMS, Rishikesh - 249 203, Uttarakhand
India

About 30% of all newly diagnosed renal cell carcinoma (RCC) patients present with synchronous metastatic disease. Usual organs of involvement are lung (75%), soft tissues (36%), bone (20%), liver (18%), cutaneous sites (8%), and central nervous system (8%). Metastases to the paranasal sinuses (PNS) are relatively common and may be a part of synchronous multiorgan involvement or present in follow-up after radical nephrectomy (metachronous); but primary presentation as isolated paranasal mass before the diagnosis of RCC is extremely rare. Here, we report a case of 74-year-old female presented with epistaxis and nasal obstruction. On evaluation by magnetic resonance imaging (MRI), a heterogeneously enhancing mass was found involving left PNS. Biopsy from mass revealed clear cell RCC. Later on, contrast-enhanced computed tomography (CECT) of chest, abdomen, and pelvis showed enhancing mass from the upper pole of the left kidney with no evidence of metastasis elsewhere. The patient was started on pazopanib 800 mg once a day. At 6 months follow-up scan, there was a partial response at both primary as well as metastatic site.


How to cite this article:
Ranjan SK, Mittal A, Kumar S, Mammen KJ, Navariya SC, Bhirud DP. Epistaxis presenting as sentinel feature of metastatic renal cell carcinoma: A case report and review of literature.J Family Med Prim Care 2020;9:3766-3769


How to cite this URL:
Ranjan SK, Mittal A, Kumar S, Mammen KJ, Navariya SC, Bhirud DP. Epistaxis presenting as sentinel feature of metastatic renal cell carcinoma: A case report and review of literature. J Family Med Prim Care [serial online] 2020 [cited 2021 May 15 ];9:3766-3769
Available from: https://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=7;spage=3766;epage=3769;aulast=Ranjan;type=0