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  Indian J Med Microbiol
 

Figure 1: Discriminatory clinical features indicating the most probable etiology in patients with primary amenorrhea. aExcluding patients with obvious etiology at presentation (e.g. Chemotherapy or autoimmune disorder related premature ovarian insufficiency, Chronic illness) or with features of virilization/genital ambiguity (partial AIS, CAH, DSDs). Abbreviations: CAIS Complete Androgen Insensitivity Syndrome; B3 Breast Tanner stage 3; P2 Pubic hair Tanner stage 2; PCOS Polycystic Ovarian Syndrome; HPrl Hyperprolactinemia; HH Hypogonadotropic Hypogonadism; GDXX XX Gonadal Dysgenesis,bFew HH patients may have progesterone withdrawalcPatients with delayed puberty have early presentation (Mean age: 15.5 y) and LH response to GnRH stimulation is optimal

Figure 1: Discriminatory clinical features indicating the most probable etiology in patients with primary amenorrhea. <sup>a</sup>Excluding patients with obvious etiology at presentation (e.g. Chemotherapy or autoimmune disorder related premature ovarian insufficiency, Chronic illness) or with features of virilization/genital ambiguity (partial AIS, CAH, DSDs). Abbreviations: CAIS Complete Androgen Insensitivity Syndrome; B3 Breast Tanner stage 3; P2 Pubic hair Tanner stage 2; PCOS Polycystic Ovarian Syndrome; HPrl Hyperprolactinemia; HH Hypogonadotropic Hypogonadism; GDXX XX Gonadal Dysgenesis,<sup>b</sup>Few HH patients may have progesterone withdrawal<sup>c</sup>Patients with delayed puberty have early presentation (Mean age: 15.5 y) and LH response to GnRH stimulation is optimal